Case study
Delivering personalized supply chains for autologous cell therapies
Cell and gene therapies have the power to revolutionize treatment for many diseases. These advanced therapies are fragile, highly sensitive to the environment and are personalized to the individual.
The ability to overcome these complex challenges is critical when managing cell and gene therapy supply chains.
Personalized medicine requires personalized transportation - an approach to logistics as revolutionary as the therapies it delivers.
The customer, based in the United States, develops cell therapy platforms for a variety of solid tumors. Biocair was contacted to collect and transport the cells to the manufacturing site in Europe, and then ship them back to the patients.
Customer
A clinical-stage biopharmaceutical company
Challenge
To develop an end-to-end logistics solution for an autologous study
Solution
Next Flight Out service with complete chain of custody and identity
Locations
Challenges
Ensuring chain of identity and custody for a cell therapy supply chain
Given that cell and gene therapies are living drug products with complex demands, including short life spans and narrow treatment parameters, it was essential to provide real-time information regarding a shipment’s location and condition, helping to ensure safe delivery of these critical materials.
The need for contingency planning throughout
Delivering cells successfully can often be a complex, multi-step process. This particular application included a number of manufacturing and patient sites across a variety of locations globally.
Due to the complex nature of this study, and uncontrollable incidents that may arise such as the reduced flight options and changing flight schedules caused by the ongoing COVID-19 pandemic, Biocair’s logistics experts had to mitigate potential issues, devising and monitoring alternate supply routes in advance of transportation.
Solution
Utilizing the latest temperature-controlled packaging and monitoring technologies
Taking into account the requirement to monitor location and condition in real-time, Biocair provided liquid nitrogen dewars with remote condition monitoring and GPS positioning. These state of the art dewars form a network of strategically located liquid nitrogen facilities worldwide.
Cryogenic shipping ensures safe delivery of the invaluable cryomaterials
Implementing a chain of custody and identity
Biocair managed chain of custody for each shipment, ensuring details such as the name of the driver, collection date and subsequent handovers were recorded throughout the study.
24/7 support and project management by a team of industry experts
Biocair’s team of cell and gene therapy logistics experts provided around the clock support to the customer. During set up the team also arranged for on-site demonstrations and training, ensuring that each site was familiar in the handling of the study procedures, packaging and requirements.
The team then monitored every shipment - checking location, orientation and temperature - and liaised with Biocair’s drivers for real-time updates on progress to ensure absolute peace of mind of location and condition, guaranteeing the safe delivery of life-saving materials.
To maximize our ability to address the challenges surrounding the shipment of cells, we are working with Biocair as our shipping logistics and chain of custody partner.
Biocair has reliably delivered these living products without diminishing their quality. We have benefited from the real-time tracking of shipments that Biocair provides.
A customer spokesperson
Summary
By implementing a collaborative approach working directly with key stakeholders, Biocair’s dedicated team of experts designed a personalized supply chain to support the development of the client’s innovative cell and gene therapies.
Personalized service is vital when transporting samples that are irreplaceable, invaluable and unique to that individual.
Do you need support with your cell therapy supply chain? Find out how Biocair can help.
Get in touch with our experts
Wherever you are located in the world, our team of experts are on hand to support your supply chain.
